11th ISABS Conference

Welcome to the web page of the Eleventh ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine

Split, Republic of Croatia
June 17-22, 2019

11th ISABS Conference Invited speakers:

Nobel Laureate Lectures:
Avram Hershko (Nobel Prize in Chemistry 2004, The Rappaport Faculty of Medicine, Technion -Israel Institute of Technology, Haifa, Israel): The ubiquitin system for protein degradation: some roles in health and disease
Robert Huber (Nobel Prize in Chemistry 1988, Max-Planck-Institut für Biochemie, Technische Universität München, Universität Duisburg-Essen, Germany): New Ways of Vision: Protein Structures in Translational Medicine and Business Development, my Experience
Paul Modrich (Nobel Prize in Chemistry 2015, Duke University Medical Center, Durham, NC, USA): Mechanisms in human DNA mismatch repair
Ada Yonath (Nobel Prize in Chemistry 2009, Weizmann Institute of Science, Rehovot, Israel): The ribosome - a connection between the prebiotic origin of life and next generation antibiotics

Individualized Medicine Program:
Ryan C. Bailey (University of Michigan, Ann Arbor, MI, USA): New microfluidic tools for high throughput and low input epigenomic studies
Arnold I. Caplan (Case Western Reserve University, Cleveland, OH, USA): Mesenchymal stem cells: time to change the name
Luis A. Diaz, Jr. (Memorial Sloan Kettering Cancer Center, New York, NY, USA): Clinical applications of circulating tumor DNA
Henry A. Erlich (Children's Hospital Oakland Research Institute, Oakland, CA, USA): Next-generation sequencing for non-invasive prenatal diagnosis of the hemoglobinopathies: a model for autosomal recessive diseases
Magnus Essand (Uppsala University, Uppsala, Sweden): Cancer immunotherapy using genetically engineered viruses and immune cells
Nilufer Ertekin-Taner (Mayo Clinic, Jacksonville, FL, USA): Comparative – omics in neurodegenerative diseases: pathways of convergence and divergence
Mark A. Frye (Mayo Clinic, Rochester, MN, USA): Epigenetics in bipolar disorder
Arezou A. Ghazani (Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA): Increasing clinical utility of large scale sequencing in the precision medicine era
Haojie Huang (Mayo Clinic, Rochester, MN, USA): Gene mutation, epigenetic rewiring and therapy resistance in cancer
Wolfgang Janni (University of Ulm, Ulm, Germany): Clinical utility of circulating tumor cells in early and advanced breast cancer
Manolis Kellis (Massachusetts Institute of Technology, The Broad Institute, Cambridge, MA, USA): From genomics to therapeutics: dissection and manipulation of human disease circuitry at single-cell resolution
John B. Kisiel (Mayo Clinic, Rochester, MN, USA): Liquid biopsy for early detection of cancer: recent advances and key challenges
Eric W. Klee (Mayo Clinic, Rochester, MN, USA): RNA assisted diagnostics and novel therapeutics
Gordan Lauc (University of Zagreb; Genos Ltd., Zagreb, Croatia): Glycans as biomarkers and functional effectors in diabetes and cardiovascular diseases
Minetta C. Liu (Mayo Clinic, Rochester, MN, USA): Development of CTC and CFDNA based assays for the management of solid tumors
Raul Mostoslavsky (Massachusetts General Hospital, Harvard Medical School, The Broad Institute, Boston, MA, USA): Linking cancer, epigenetics, and metabolism: lessons from SIRT6
Grzegorz S. Nowakowski (Mayo Clinic, Rochester, MN, USA): Personalized therapy of lymphoma – reversal of translation
Tamas Ordog (Mayo Clinic, Rochester, MN, USA): Interrogating and manipulating lineage-critical enhancers for therapeutic benefit
Dragan Primorac (The Pennsylvania State University and University of New Haven, USA; St. Catherine Hospital, Children's Hospital "Srebrnjak", Zagreb, Croatia; Universities of Split, Rijeka and Osijek, Croatia): Articular cartilage regeneration: current and future technologies
Thereasa Rich (Guardant Health, Redwood City, CA, USA): Analytical and clinical validation of a comprehensive cell-free circulating tumor genotyping assay
Keith D. Robertson (Mayo Clinic, Rochester, MN, USA): Identifying and targeting epigenetic defects in liver disease
Jacques Schrenzel (Geneva University Hospitals, Geneva, Switzerland): Microbiome analysis in clinical medicine: hope or hype?
Keith Stewart (Mayo Clinic, Rochester, MN, USA): Individualized medicine 2019
Christoph A. Thaiss (University of Pennsylvania, Philadelphia, PA, USA): Microbiome dynamics in obesity
Raul A. Urrutia (Medical College of Wisconsin, Milwaukee, WI, USA): Epigenomics of pancreatic cancer
George Vasmatzis (Mayo Clinic, Rochester, MN, USA): Personalized therapy monitoring and relapse detection strategies using abnormal tumor-related DNA junctions
Richard Weinshilboum (Mayo Clinic, Rochester, MN, USA): Genes and drug response: an Odyssey
Andre van Wijnen (Mayo Clinic, Rochester, MN, USA): Osteogenic programming by inhibiting epigenetic suppression
Rugang Zhang (The Wistar Institute, Philadelphia, PA, USA): Personalized therapeutic approaches to SWI/SNF alterations in ovarian cancer
Zhiguo Zhang (Columbia University, New York, NY, USA): Epigenetic alterations in glioma

Forensic Genetics and Anthropological Genetics Program:
Joshua Akey (Princeton University, Princeton, NJ, USA): Archaic human DNA in the genome of modern humans
Frederick Bieber (Harvard University, Cambridge, MA, USA): Genealogics rides the three-horse chariot of the criminal justice system
Joachim Burger (University of Mainz, Germany): Demographic and evolutionary inference from palaeogenomes
Yaniv Erlich (Columbia University, New York, NY, USA): Long range familial searches: treat lightly!
Tom Gilbert (University of Copenhagen, Copenhagen, Denmark): Population palaeogenomics and the consequences of the second plague pandemic
Catarina Gomes Alves Xavier (Medical University Innsbruck, Innsbruck, Austria): Development and validation of prototype MPS tools to infer appearance, ancestry, and age from forensic DNA samples
Wolfgang Haak (Max Planck Institute for the Science of Human History, Jena, Germany): Into the great wide open: 3000 years of human population history in the Caucasus region
Bastiaan Heijmans (Leiden University Medical Center, Leiden, Netherlands): Cross-omics analysis in populations to understand the role of epigenomic change in human ageing
Mitchell M. Holland (The Pennsylvania State University, University Park, State College, PA, USA): DCMPS of mtDNA heteroplasmy: an established tool for forensic investigations
Jodi Irwin (Federal Bureau of Investigation, Quantico, VA, USA): MPS implementation in forensic casework
Mattias Jakobsson (Uppsala University, Uppsala, Sweden): Ancient genomes from Southern Africa push modern human emergence to 300,000 years ago
Manfred Kayser (Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands): Improving forensic Y-STR and Y-SNP analysis
Michael S. Kobor (University of British Columbia, Vancouver, BC, Canada): Environmental factors shaping the human epigenome
Johannes Krause (Max Planck Institute for the Science of Human History, Jena, Germany): The genetic history of the plague: from the Stone Age to the 18th century
James Landers (University of Virginia School of Medicine, Charlottesville, VA, USA): Microfluidics: science, technology, and applications in forensics and medicine
Henry Lee (University of New Haven, New Haven, CT, USA): Fire and Explosion Investigation and Forensic Analysis
Simon Mead (University College London Hospitals, London, United Kingdom): Genetic adaptation to prion diseases with a particular reference to Kuru in Papua New Guinea and CJD in Europe
Matthias Meyer (Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany): Reconstructing ancient DNA fragments on a single-molecule level
Ludovic Orlando (University of Toulouse, Toulouse, France):  Mapping DNA methylation and nucleosomal positions in ancient individuals
Daniele Podini (George Washington University, Washington D.C., USA): Microhaplotypes: a comprehensive forensic DNA marker
Noah Rosenberg (Stanford University, Stanford, USA): Matching DNA records with disjoint sets of genetic markers
Antti Sajantila (University of Helsinki, Helsinki, Finland): Use of human and virus DNA for assessing ancestry in forensic and archaeological context
Viviane Slon (Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany): Inferring interactions between Neanderthals and Denisovans from ancient DNA
Anne Stone (Arizona State University, Tempe, AZ, USA): Tracking a killer: using ancient DNA to understand the evolutionary history of Mycobacterium tuberculosis
Mark Thomas (University College London, London, United Kingdom): Genetic astrology
Zhenjiang Xu (Nanchang University, Nanchang, China): Accurate estimates of the post-mortem interval using cadaver-associated microbiomes
Hwan Young Lee (Seoul National University College of Medicine, Seoul, South Korea): Epigenetic age signatures in bones

Interdisciplinary Session of American Academy of Forensic Sciences and ISABS 2019:
Peter Ausili (US Drug Enforcement Administration (Retired), Chicago, IL, USA): Challenging expert witnesses in drug cases
Robert Barsley (LSU Health Science Center, School of Dentistry, Dept of Diagnostic Sciences, New Orleans, LA USA): Forensic bitemark evidence in court
Zeno Geradts (Netherlands Forensic Institute of the Ministry of Justice and University of Amsterdam, Amsterdam, Netherlands): Using Artificial Intelligence in Forensic Science
Samiah Ibrahim (American Academy of Forensic Sciences, Questioned Documents Section, Colorado Springs, CO, USA): Forensic intelligence: application of interdisciplinary data for law enforcement purposes
Henry Lee (University of New Haven, New Haven, CT, USA): Forensic evidence and justice
Laura L. Liptai (BioMedical Forensics, Moraga, CA United States): Autonomous vehicle human factors performance in the United States including biomedical engineering analysis of fatal accidents
Virginia Lynch (Oakland University School of Nursing, Forensic Nursing Program, Rochester, MN USA): Forensic nursing science: an alliance of health and justice
Carla Noziglia (Forensic Science Matters, Aiken, South Carolina, USA): Ethics and the genomic explosion
Martin Olivier (Department of Computer Science, University of Pretoria, South Africa): Medico-legal examinations as a paradigm for digital examinations
Haskel Pitluck (Retired Circuit Court Judge, State of Illinois 19th Judical Circuit, Crystal Lake, IL, USA): Understanding of forensic expert report by judges
Giuseppe Troccoli (Mental Health Services, Bari, Italy): Forensic Psychiatry: the contribution to investigations

Round Table by ISABS, Croatian Judges Association and Croatian Academy of Legal Sciences (Croatian language):
Marta Dragicevic Prtenjaca (University of Zagreb, Zagreb, Croatia): Introduction to European innocence network - Croatian perspective (Uvod u Europsku mrežu nedužnosti - Hrvatski model)
Damir Kontrec (Supreme Court of The Republic of Croatia, Zagreb, Croatia): DNA in civilian and common law in Croatia (Analiza DNA s građansko pravnog aspekta u Hrvatskoj)
Damir Primorac (University of Split, Split, Croatia): DNA and criminal justice in Croatia (Kazneno-pravni aspekt DNA analize u Hrvatskoj)
Suncana Roksandic Vidlicka (University of Zagreb, Zagreb, Croatia): The use of DNA analysis in retrial of criminal cases in Croatia (Analiza DNA tijekom obnove pravomoćno okončanog kaznenog postupka - Hrvatska praksa)

Human Glycome Project
Yurii Aulchenko (Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia): Genes regulating variation of protein N-glycosilation in human populations
Richard Cummings (Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Medical School, Boston, MA, US) – moderator
Richard Cummings (Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, US): Human Glycome Project – important outcomes for glycomics, development, immunology, and infectious disease
Richard Drake (Medical University of South Carolina, Charleston, SC, USA): Reproducibility and portability of solid-phase N-glycan MALDI profiling workflows for tissues, cells and biofluids
Sabine Flitsch (University of Manchester, Manchester, United Kingdom): The use of enzymes in glycoengineering
Michael Hawkeye Pierce (University of Georgia, Athens, GA, USA): A targeted approach to determining the human glycome
Mike Tiemeyer (University of Georgia, Athens, GA, USA): The glycomic diversity of homogenous human cell populations derived from pluripotent precursors
Vlatka Zoldos (University of Zagreb, Zagreb, Croatia): CRISPR/CAS9 for epigenetic editing: an application in studies of aberrant protein glycosylation in complex diseases
Manfred Wuhrer (Leiden University Medical School, Leiden, The Netherlands): Glycomics of cancer and autoimmune diseases

Joint Session: ISABS, Regiomed Kliniken, Germany, University of Split, Croatia (By Invitation)
Johannes Brachmann (Regiomed Kliniken, Coburg, Germany): Emerging role of precision medicine in cardiovascular disease
Zoran Dogas (University of Split School of Medicine, Split, Croatia): Diabetes and sleep: a novel approach in precision medicine

Philips Personalised Medicine Session
Jan L.L. Kimpen (Philips Center, Amsterdam, the Netherlands): Innovation and the future of healthcare – technology breaking down silos