11th Conference Invited Speakers

Nobel Laureate Lectures:
Avram Hershko (Nobel Prize in Chemistry 2004, The Rappaport Faculty of Medicine, Technion -Israel Institute of Technology, Haifa, Israel): The ubiquitin system for protein degradation: some roles in health and disease
Robert Huber (Nobel Prize in Chemistry 1988, Max-Planck-Institut für Biochemie, Technische Universität München, Universität Duisburg-Essen, Germany): New Ways of Vision: Protein Structures in Translational Medicine and Business Development, my Experience
Paul Modrich (Nobel Prize in Chemistry 2015, Duke University Medical Center, Durham, NC, USA): Mechanisms in human DNA mismatch repair
Ada Yonath (Nobel Prize in Chemistry 2009, Weizmann Institute of Science, Rehovot, Israel): The ribosome - a connection between the prebiotic origin of life and next generation antibiotics

Individualized Medicine Program:
Ryan C. Bailey (University of Michigan, Ann Arbor, MI, USA): New microfluidic tools for high throughput and low input epigenomic studies
Arnold I. Caplan (Case Western Reserve University, Cleveland, OH, USA): Mesenchymal stem cells: time to change the name
Luis A. Diaz, Jr. (Memorial Sloan Kettering Cancer Center, New York, NY, USA): Clinical applications of circulating tumor DNA
Henry A. Erlich (Children's Hospital Oakland Research Institute, Oakland, CA, USA): Next-generation sequencing for non-invasive prenatal diagnosis of the hemoglobinopathies: a model for autosomal recessive diseases
Magnus Essand (Uppsala University, Uppsala, Sweden): Cancer immunotherapy using genetically engineered viruses and immune cells
Nilufer Ertekin-Taner (Mayo Clinic, Jacksonville, FL, USA): Comparative – omics in neurodegenerative diseases: pathways of convergence and divergence
Mark A. Frye (Mayo Clinic, Rochester, MN, USA): Epigenetics in bipolar disorder
Arezou A. Ghazani (Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA): Increasing clinical utility of large scale sequencing in the precision medicine era
Haojie Huang (Mayo Clinic, Rochester, MN, USA): Gene mutation, epigenetic rewiring and therapy resistance in cancer
Wolfgang Janni (University of Ulm, Ulm, Germany): Clinical utility of circulating tumor cells in early and advanced breast cancer
Manolis Kellis (Massachusetts Institute of Technology, The Broad Institute, Cambridge, MA, USA): From genomics to therapeutics: dissection and manipulation of human disease circuitry at single-cell resolution
John B. Kisiel (Mayo Clinic, Rochester, MN, USA): Liquid biopsy for early detection of cancer: recent advances and key challenges
Eric W. Klee (Mayo Clinic, Rochester, MN, USA): RNA assisted diagnostics and novel therapeutics
Gordan Lauc (University of Zagreb; Genos Ltd., Zagreb, Croatia): Glycans as biomarkers and functional effectors in diabetes and cardiovascular diseases
Minetta C. Liu (Mayo Clinic, Rochester, MN, USA): Development of CTC and CFDNA based assays for the management of solid tumors
Raul Mostoslavsky (Massachusetts General Hospital, Harvard Medical School, The Broad Institute, Boston, MA, USA): Linking cancer, epigenetics, and metabolism: lessons from SIRT6
Grzegorz S. Nowakowski (Mayo Clinic, Rochester, MN, USA): Personalized therapy of lymphoma – reversal of translation
Tamas Ordog (Mayo Clinic, Rochester, MN, USA): Interrogating and manipulating lineage-critical enhancers for therapeutic benefit
Dragan Primorac (The Pennsylvania State University and University of New Haven, USA; St. Catherine Hospital, Children's Hospital "Srebrnjak", Zagreb, Croatia; Universities of Split, Rijeka and Osijek, Croatia): Articular cartilage regeneration: current and future technologies
Thereasa Rich (Guardant Health, Redwood City, CA, USA): Analytical and clinical validation of a comprehensive cell-free circulating tumor genotyping assay
Keith D. Robertson (Mayo Clinic, Rochester, MN, USA): Identifying and targeting epigenetic defects in liver disease
Jacques Schrenzel (Geneva University Hospitals, Geneva, Switzerland): Microbiome analysis in clinical medicine: hope or hype?
Keith Stewart (Mayo Clinic, Rochester, MN, USA): Individualized medicine 2019
Christoph A. Thaiss (University of Pennsylvania, Philadelphia, PA, USA): Microbiome dynamics in obesity
Raul A. Urrutia (Medical College of Wisconsin, Milwaukee, WI, USA): Epigenomics of pancreatic cancer
George Vasmatzis (Mayo Clinic, Rochester, MN, USA): Personalized therapy monitoring and relapse detection strategies using abnormal tumor-related DNA junctions
Richard Weinshilboum (Mayo Clinic, Rochester, MN, USA): Genes and drug response: an Odyssey
Andre van Wijnen (Mayo Clinic, Rochester, MN, USA): Osteogenic programming by inhibiting epigenetic suppression
Rugang Zhang (The Wistar Institute, Philadelphia, PA, USA): Personalized therapeutic approaches to SWI/SNF alterations in ovarian cancer
Zhiguo Zhang (Columbia University, New York, NY, USA): Epigenetic alterations in glioma

Forensic Genetics and Anthropological Genetics Program:
Joshua Akey (Princeton University, Princeton, NJ, USA): Archaic human DNA in the genome of modern humans
Frederick Bieber (Harvard University, Cambridge, MA, USA): Genealogics rides the three-horse chariot of the criminal justice system
Joachim Burger (University of Mainz, Germany): Demographic and evolutionary inference from palaeogenomes
Yaniv Erlich (Columbia University, New York, NY, USA): Long range familial searches: treat lightly!
Tom Gilbert (University of Copenhagen, Copenhagen, Denmark): Population palaeogenomics and the consequences of the second plague pandemic
Catarina Gomes Alves Xavier (Medical University Innsbruck, Innsbruck, Austria): Development and validation of prototype MPS tools to infer appearance, ancestry, and age from forensic DNA samples
Wolfgang Haak (Max Planck Institute for the Science of Human History, Jena, Germany): Into the great wide open: 3000 years of human population history in the Caucasus region
Bastiaan Heijmans (Leiden University Medical Center, Leiden, Netherlands): Cross-omics analysis in populations to understand the role of epigenomic change in human ageing
Mitchell M. Holland (The Pennsylvania State University, University Park, State College, PA, USA): DCMPS of mtDNA heteroplasmy: an established tool for forensic investigations
Jodi Irwin (Federal Bureau of Investigation, Quantico, VA, USA): MPS implementation in forensic casework
Mattias Jakobsson (Uppsala University, Uppsala, Sweden): Ancient genomes from Southern Africa push modern human emergence to 300,000 years ago
Manfred Kayser (Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands): Improving forensic Y-STR and Y-SNP analysis
Michael S. Kobor (University of British Columbia, Vancouver, BC, Canada): Environmental factors shaping the human epigenome
Johannes Krause (Max Planck Institute for the Science of Human History, Jena, Germany): The genetic history of the plague: from the Stone Age to the 18th century
James Landers (University of Virginia School of Medicine, Charlottesville, VA, USA): Microfluidics: science, technology, and applications in forensics and medicine
Henry Lee (University of New Haven, New Haven, CT, USA): Fire and Explosion Investigation and Forensic Analysis
Simon Mead (University College London Hospitals, London, United Kingdom): Genetic adaptation to prion diseases with a particular reference to Kuru in Papua New Guinea and CJD in Europe
Matthias Meyer (Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany): Reconstructing ancient DNA fragments on a single-molecule level
Ludovic Orlando (University of Toulouse, Toulouse, France):  Mapping DNA methylation and nucleosomal positions in ancient individuals
Daniele Podini (George Washington University, Washington D.C., USA): Microhaplotypes: a comprehensive forensic DNA marker
Noah Rosenberg (Stanford University, Stanford, USA): Matching DNA records with disjoint sets of genetic markers
Antti Sajantila (University of Helsinki, Helsinki, Finland): Use of human and virus DNA for assessing ancestry in forensic and archaeological context
Viviane Slon (Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany): Inferring interactions between Neanderthals and Denisovans from ancient DNA
Anne Stone (Arizona State University, Tempe, AZ, USA): Tracking a killer: using ancient DNA to understand the evolutionary history of Mycobacterium tuberculosis
Mark Thomas (University College London, London, United Kingdom): Genetic astrology
Zhenjiang Xu (Nanchang University, Nanchang, China): Accurate estimates of the post-mortem interval using cadaver-associated microbiomes
Hwan Young Lee (Seoul National University College of Medicine, Seoul, South Korea): Epigenetic age signatures in bones

Interdisciplinary Session of American Academy of Forensic Sciences and ISABS 2019:
Peter Ausili (US Drug Enforcement Administration (Retired), Chicago, IL, USA): Challenging expert witnesses in drug cases
Robert Barsley (LSU Health Science Center, School of Dentistry, Dept of Diagnostic Sciences, New Orleans, LA USA): Forensic bitemark evidence in court
Zeno Geradts (Netherlands Forensic Institute of the Ministry of Justice and University of Amsterdam, Amsterdam, Netherlands): Using Artificial Intelligence in Forensic Science
Samiah Ibrahim (American Academy of Forensic Sciences, Questioned Documents Section, Colorado Springs, CO, USA): Forensic intelligence: application of interdisciplinary data for law enforcement purposes
Henry Lee (University of New Haven, New Haven, CT, USA): Forensic evidence and justice
Laura L. Liptai (BioMedical Forensics, Moraga, CA United States): Autonomous vehicle human factors performance in the United States including biomedical engineering analysis of fatal accidents
Virginia Lynch (Oakland University School of Nursing, Forensic Nursing Program, Rochester, MN USA): Forensic nursing science: an alliance of health and justice
Carla Noziglia (Forensic Science Matters, Aiken, South Carolina, USA): Ethics and the genomic explosion
Martin Olivier (Department of Computer Science, University of Pretoria, South Africa): Medico-legal examinations as a paradigm for digital examinations
Haskel Pitluck (Retired Circuit Court Judge, State of Illinois 19th Judical Circuit, Crystal Lake, IL, USA): Understanding of forensic expert report by judges
Giuseppe Troccoli (Mental Health Services, Bari, Italy): Forensic Psychiatry: the contribution to investigations

Round Table by ISABS, Croatian Judges Association and Croatian Academy of Legal Sciences (Croatian language):
Marta Dragicevic Prtenjaca (University of Zagreb, Zagreb, Croatia): Introduction to European innocence network - Croatian perspective (Uvod u Europsku mrežu nedužnosti - Hrvatski model)
Damir Kontrec (Supreme Court of The Republic of Croatia, Zagreb, Croatia): DNA in civilian and common law in Croatia (Analiza DNA s građansko pravnog aspekta u Hrvatskoj)
Damir Primorac (University of Split, Split, Croatia): DNA and criminal justice in Croatia (Kazneno-pravni aspekt DNA analize u Hrvatskoj)
Suncana Roksandic Vidlicka (University of Zagreb, Zagreb, Croatia): The use of DNA analysis in retrial of criminal cases in Croatia (Analiza DNA tijekom obnove pravomoćno okončanog kaznenog postupka - Hrvatska praksa)

Human Glycome Project
Yurii Aulchenko (Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia): Genes regulating variation of protein N-glycosilation in human populations
Richard Cummings (Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Medical School, Boston, MA, US) – moderator
Richard Cummings (Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, US): Human Glycome Project – important outcomes for glycomics, development, immunology, and infectious disease
Richard Drake (Medical University of South Carolina, Charleston, SC, USA): Reproducibility and portability of solid-phase N-glycan MALDI profiling workflows for tissues, cells and biofluids
Sabine Flitsch (University of Manchester, Manchester, United Kingdom): The use of enzymes in glycoengineering
Michael Hawkeye Pierce (University of Georgia, Athens, GA, USA): A targeted approach to determining the human glycome
Mike Tiemeyer (University of Georgia, Athens, GA, USA): The glycomic diversity of homogenous human cell populations derived from pluripotent precursors
Vlatka Zoldos (University of Zagreb, Zagreb, Croatia): CRISPR/CAS9 for epigenetic editing: an application in studies of aberrant protein glycosylation in complex diseases
Manfred Wuhrer (Leiden University Medical School, Leiden, The Netherlands): Glycomics of cancer and autoimmune diseases

Joint Session: ISABS, Regiomed Kliniken, Germany, University of Split, Croatia (By Invitation)
Johannes Brachmann (Regiomed Kliniken, Coburg, Germany): Emerging role of precision medicine in cardiovascular disease
Zoran Dogas (University of Split School of Medicine, Split, Croatia): Diabetes and sleep: a novel approach in precision medicine

Philips Personalised Medicine Session
Jan L.L. Kimpen (Philips Center, Amsterdam, the Netherlands): Innovation and the future of healthcare – technology breaking down silos